Alexis S. Ivanov

Intermolecular interactions of CYP3A enzymes and cytosolic sulfotransferases (SULT1E1, SULT2A1)

This study identifies direct physical interactions between CYP3A4/3A5 and SULT1E1/2A1 using SPR, activity assays, and AlphaFold2 modeling, revealing potential substrate channeling mechanisms.

Diverse Ligands for Mycobacterial CYP124 Identified from Plant and Marine Compounds

The paper identifies nine novel non-azole ligands for Mycobacterium tuberculosis CYP124 from plant and marine compounds, revealing potential for mechanism-based tuberculosis inhibitors.

Substrate-induced modulation of protein-protein interactions within human mitochondrial cytochrome P450-dependent system

The paper investigates how steroid substrates modulate protein-protein interactions between adrenodoxin and mitochondrial CYP11s, revealing isoform-specific effects on complex formation and stability.