Structural basis of tRNA recognition by the m3C-RNA-methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase
Philipp Throll, Luciano G. Dolce, Palma Rico-Lastres, Katharina Arnold, Laura Tengo, Shibom Basu, Stefanie Kaiser, Robert Schneider, Eva Kowalinski
The paper reports the cryo-EM structure of METTL6 in complex with SerRS and tRNASer, revealing their interaction and methylation mechanism.
Nature Structural & Molecular Biology · Jun 25, 2024Peer-reviewedMolecular Biology