Eva Kowalinski

This study identifies a direct interaction between the RNA helicase KREH2 and the RESC1-RESC2 complex in trypanosomatid mitochondrial RNA editing using biochemical and structural methods.

This study investigates the role of KREH1's C-terminus in RNA binding and its interaction with mitochondrial RNA editing complexes in T. brucei.

This study defines the mechanism by which METTL6 and SerRS cooperatively recognize and catalyze tRNA m3C methylation using simulations and in vitro experiments.

The paper reports the cryo-EM structure of METTL6 in complex with SerRS and tRNASer, revealing their interaction and methylation mechanism.

This paper reports cryo-EM structures of the Trypanosoma brucei cap-binding complex (TbCBC) and identifies its interactions with the spliced leader RNA.

The paper reports the cryo-EM structure of the RESC1-RESC2 complex from Trypanosoma brucei, revealing its role in guide RNA selection through 5-triphosphate binding.

This study presents the first structure of a eukaryotic ADAT2/3 deaminase bound to tRNA, revealing sequence-independent substrate selection and a novel gating mechanism for substrate entry.