The eIF3a subunit drives RNA binding within the eIF3 complex
Nicholas A. Ide, Riley C. Gentry, Brennan Ashwood, Margaret A Rudbach, Kyungyoon Yoo, Paloma Kai Velez, Victoria M Communale, Erik W. Hartwick, Colin D. Kinz-Thompson, Ruben L. Gonzalez, Colin Echeverría Aitken
This study reconstitutes a biochemically active yeast eIF3 complex and shows that eIF3a provides core RNA-binding activity, modulated by interactions with other subunits.
bioRxiv · Apr 25, 2024 · PreprintBiophysics