MYC pathway reprogramming through a TIP60 coactivator switch in neuroendocrine lineage transition in prostate cancer
Zhen Sun, Jimmy Zhao, Zahra Khan, Wazim Mohammed Ismail, Teng Han, Subhiksha Nandakumar, Serina Young, Matthew Lange, Pan Cheng, Richard P. Koche, Nikolaus Schultz, Alexandre Gaspar‐Maia, Charles L. Sawyers
The paper identifies a TIP60 coactivator switch in neuroendocrine prostate cancer, revealing a therapeutic target for MYC-driven diseases.
bioRxiv · May 8, 2026 · PreprintCancer Biology