High-Throughput Screening on Primary Tumor-Associated Microglia and Macrophages Identifies HDAC Inhibitors as Enhancers of Phagocytosis and Potent Partners for Immunotherapy in Glioblastoma
Mona Khalaj, Madison L. Gutierrez, Parisa Nejad, Tal Bachar Raveh, Faranak Fattahi, Irving L. Weissman
This study identifies HDAC inhibitors as enhancers of TAM phagocytosis and synergistic partners for immunotherapy in GBM through high-throughput screening.
bioRxiv · Mar 24, 2025 · PreprintCancer Biology