Author

Patrick da Silva

Harvard UniversityPrimary ORCID profile (0000-0002-3481-4972 · 3 papers)Unclaimed ORCID profile · follow to get notified of new preprints

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Patrick da SilvaiD3 papers · Brigham and Women's Hospital

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Bernardo de Castro OliveiraiD· 1 shared Bianca Vieira dos Santos· 1 shared Bruno Montanari BorgesiD· 1 shared Bruno Prado Eleuterio· 1 shared C. A. D. TeixeiraiD· 1 shared Carlos Neandro Cordeiro LimaiD· 1 shared Denise Morais da FonsecaiD· 1 shared Dennyson Leandro M. FonsecaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

Bernardo de Castro OliveiraORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Single-cell RNA sequencing of CTLA-4 and PD-1 blockade in pulmonary paracoccidioidomycosis highlights a protective transcriptional program mediated by activated Th17 cells, neutrophils and macrophages

Sandra Márcia Muxel, Dennyson Leandro M. Fonseca, Ian Antunes Ferreira Bahia, Patrick da Silva, Leonardo Mandu Gonçalves, Emanuella Sarmento Alho de Sousa, Jonathan Miguel Zanatta, C. A. D. Teixeira, Kathi Terumi Kato, Manoela Osorio R Sales, Carlos Neandro Cordeiro Lima, Bruno Prado Eleuterio, Luciana dos Santos Barros Manhães, Bernardo de Castro Oliveira, Nycolas Willian Preite, , Vera Lúcia Garcia Calich

This study uses single-cell RNA sequencing to show that checkpoint inhibitors like anti-CTLA-4 and anti-PD-1 shift the lung immune response in PCM toward a Th17-driven program involving neutrophils and macrophages, enhancing antifungal immunity.

bioRxiv · Jan 23, 2026 · PreprintImmunology