Author

Patrick Seigneur

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Alexandrine Rozié· 1 shared Bastien DumaisiD· 1 shared Dennis GómeziD· 1 shared Luce Fontanié--Roger· 1 shared Madeleine BossaertiD· 1 shared Maëlle CaroffiD· 1 shared Philippe FritiD· 1 shared Sébastien BrittoniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Alexandrine Rozié

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1 paper

Recent·Most cited

Exploiting HSD17B11-dependent dialkynylcarbinols cytotoxicity for facile CRISPR/Cas9-based gene inactivation

Bastien Dumais, Madeleine Bossaert, Patrick Seigneur, Alexandrine Rozié, Sophie Gasmi, Luce Fontanié--Roger, Maëlle Caroff, Valérie Maraval, Vania Bernardes‐Génisson, Dennis Gómez, Philippe Frit, Stéphanie Ballereau, Yves Génisson, Sébastien Britton

The paper demonstrates that inactivating HSD17B11 confers resistance to PAC, enabling efficient CRISPR/Cas9-based gene inactivation through PAC selection.

bioRxiv · Sep 20, 2026 · PreprintMolecular Biology