Author

Patrycja Wypych

Radboud University Nijmegen

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Neuroscience· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:non-human primate· 1

Frequent Co-Authors

Alessandro VitrioloiD· 1 shared Annika MordeltiD· 1 shared Astrid R. Oudakker· 1 shared Aurelio OrtaleiD· 1 shared Carlo Emanuele VillaiD· 1 shared Cedric A. BoeckxiD· 1 shared Chantal SchoenmakeriD· 1 shared Davide AprileiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Alessandro VitrioloORCID

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1 paper

Recent·Most cited

Human-Specific Regulation of CHD2 Controls the Tempo of Cortical Development through Lysosomal Homeostasis

Oliviero Leonardi, Elly Lewerissa, Davide Aprile, Tahsin Stefan Barakat, Lorenza Culotta, Ruizhi Deng, Linda Haazen, Katrin Linda, Marian Majoie, Annika Mordelt, Aurelio Ortale, Astrid R. Oudakker, Filippo Prazzoli, Sofía Puvogel, Nicky Scheefhals, , Nael Nadif Kasri

This study identifies a human-specific CHD2 regulatory variant that influences cortical development tempo via lysosomal homeostasis, showing therapeutic potential through lysosomal restoration.

bioRxiv · Jan 21, 2025 · PreprintNeuroscience