Author

Paul M Johnson

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:deep learning· 1

Frequent Co-Authors

Eloise G. LloydiD· 3 shared Gianluca MuccioloiD· 3 shared Giulia BiffiiD· 3 shared Joaquín Araos HenríqueziD· 3 shared Marta ZaccariaiD· 3 shared Mireia VallespinósiD· 3 shared Muntadher JihadiD· 3 shared Priscilla S.W. ChengiD· 3 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Eloise G. LloydORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

TGF-β- and IL-1-dependent fibroblast states differentially shape pancreatic cancer microenvironments and metastasis

Priscilla S.W. Cheng, Eloise G. Lloyd, Muntadher Jihad, Marta Zaccaria, Kristen Burgess, Gianluca Mucciolo, Sneha Harish, Weike Luo, Judhell S. Manansala, Wenlong Li, Joaquín Araos Henríquez, Debasmita Mukherjee, Sally Mills, Paul M Johnson, Alejandro Alonso Montero, , Giulia Biffi

This study shows that TGF-β-dependent myCAFs promote pancreatic cancer metastasis, while IL-1-dependent iCAFs do not, through distinct signaling mechanisms.

bioRxiv · Sep 10, 2026 · PreprintCancer Biology

Multi-stromal organoid co-cultures model pancreatic cancer and pancreatitis epithelial cell-fibroblast heterogeneity

Wenlong Li, Muntadher Jihad, Eloise G. Lloyd, Marta Zaccaria, Gianluca Mucciolo, Gideon Nsubuga, Alwin Koonan-Lonappan, Joaquín Araos Henríquez, Priscilla S.W. Cheng, Sneha Harish, Sally Mills, Paul M Johnson, Weike Luo, Alejandro Alonso Montero, Rebecca J. Brais, , Giulia Biffi

This study compares fibroblast heterogeneity in pancreatic cancer and pancreatitis using organoid co-cultures and identifies distinct stromal reprogramming in each condition.

Nature Cell Biology · Sep 2, 2026Peer-reviewedCancer Biology

Cross-species graph-embedding unmasks the ageing microenvironment as a key determinant of pancreatic cancer malignant cell biology and therapy response

Joaquín Araos Henríquez, Muntadher Jihad, Amir Jassim, Eloise G. Lloyd, Weike Luo, Judhell S. Manansala, Sneha Harish, Sara Pinto Teles, Priscilla S.W. Cheng, Gianluca Mucciolo, Wenlong Li, Marta Zaccaria, Debasmita Mukherjee, Rebecca J. Brais, Sally Mills, , Giulia Biffi

This study uses cross-species graph-embedding to show that ageing affects PDAC stroma and therapy response, identifying IRAK4 as a therapeutic target in aged PDAC models.

bioRxiv · Feb 3, 2026 · PreprintCancer Biology