Sex-specific regulation of macrophage function determines outcome to acute bacterial infection
Rebecca L. Belmonte, Julia Aleksandrowicz, Caroline Pumpe, Paulina Mika, Mary-Kate Corbally, David Duneau, Jennifer C. Regan
This study shows that macrophage sex identity determines infection outcomes in Drosophila, with feminized male macrophages reducing susceptibility to S. aureus.
bioRxiv · Sep 3, 2026 · PreprintImmunology