Human-specific NOTCH2NL promotes astrogenesis by expanding proliferative glial progenitor states
Riina Ishiwatari, Xuanhao D. Zhou, Rintaro Amano, Yuki Y. Yamauchi, Pauline Rouillard, Takuma Kumamoto, Yusuke Kishi, Kazuo Emoto, Ikuo Suzuki
This study identifies NOTCH2NL as a human-specific gene promoting astrocyte proliferation and gliogenesis through expansion of glial progenitor states.
bioRxiv · Dec 17, 2025 · PreprintDevelopmental Biology