Ikuo Suzuki

The paper identifies a human-specific synaptic glial precursor state by analyzing single-cell differentiation trajectories across multiple species and shows its role in human cortical evolution.

This study identifies NOTCH2NL as a human-specific gene promoting astrocyte proliferation and gliogenesis through expansion of glial progenitor states.

This study identifies three orthogonal modes of gene expression evolution in human neocortical development and links them to disease vulnerabilities.

The paper identifies mammalian-specific gene regulatory elements and their role in neocortical neuron subtype diversity and connectivity, linking them to neurodevelopmental disorders.

The paper shows that species-specific differences in cortical excitatory neuron subtypes arise from non-uniform scaling of neurogenesis timing, regulated by Wnt signaling in rats.

The paper shows that Arhgap11a mRNA localization and local translation in radial glial cells control cortical development by regulating RGC morphology and neuron positioning.

This study identifies CROCCP2 as a human-specific gene that enhances cortical progenitor expansion by modulating cilia dynamics and mTOR signalling.

The paper identifies a GGC repeat expansion in the NOTCH2NLC gene using long-read sequencing, linking it to neuronal intranuclear inclusion disease in both familial and sporadic cases.

The paper identifies hominin-specific NOTCH2 paralogs that enhance human cortical neurogenesis by modulating Delta/Notch interactions.