Intrinsic molecular susceptibility underlies selective neuronal vulnerability in the Alzheimer's disease entorhinal cortex
Samuel L Boulger, Daniela Lerose, Emily Adair, Marianna Papageorgopoulou, Yinuo Zhao, Baptiste Avot, Michael Thomas, Pavit Nibber, Hannah Klug, Nurun Nahar Fancy, Anna Mallach, Eugene Paul Duff, Alessia Caramello, Paul McMahan Matthews
The paper identifies intrinsic molecular features of calbindin-expressing neurons in the entorhinal cortex that contribute to their vulnerability in Alzheimer's disease and suggests potential therapeutic targets.
bioRxiv · Jun 26, 2026 · PreprintNeuroscience