Author

Michael Thomas

UK Dementia Research InstituteORCID 0000-0001-9511-055XUnclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Michael Thomas1 paper

Biology Disciplines

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Neuroscience· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Assay:spatial transcriptomics· 2 Research Focus:trajectory inference· 2 Research Focus:batch correction / integration· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Nurun Nahar FancyiD· 3 shared Paul McMahan MatthewsiD· 3 shared Alessia CaramelloiD· 2 shared Anna MallachiD· 2 shared Emily AdairiD· 2 shared Eugene Paul DuffiD· 2 shared Johanna JacksoniD· 2 shared Marianna PapageorgopoulouiD· 2 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersNeuroscience

Nurun Nahar FancyORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintNov 1, 2026

Neuronal and glial transcriptional states vary with proximity to tangle-bearing neurons in the human entorhinal cortex

Samuel L Boulger, Nathalie Lambie, Jan Wos…·Paul McMahan Matthews

The paper examines how proximity to tangle-bearing neurons affects transcriptional states in human entorhinal cortex cells, finding that nearby neurons and glia show distinct molecular signatures related to disease.

DOI 10.64898/2026.10.27.762234

humanspatial transcriptomics

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NeurosciencebioRxivPreprintJun 26, 2026

Intrinsic molecular susceptibility underlies selective neuronal vulnerability in the Alzheimer's disease entorhinal cortex

Samuel L Boulger, Daniela Lerose, Emily Adair…·Paul McMahan Matthews

The paper identifies intrinsic molecular features of calbindin-expressing neurons in the entorhinal cortex that contribute to their vulnerability in Alzheimer's disease and suggests potential therapeutic targets.

DOI 10.64898/2026.06.22.733753

humanspatial transcriptomics

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BioinformaticsbioRxivPreprintAug 30, 2023

Omix: A Multi-Omics Integration Pipeline

Eléonore Schneegans, Nurun Nahar Fancy, Michael Thomas…·Johanna Jackson

Omix integrates and analyzes multi-omics data to generate pseudo-temporal profiles in Alzheimer's Disease using bulk proteomics and transcriptomics datasets.

3 citations

humanbulk RNA-seq

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