Author

Pearl Chan

University of Iowa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Baek KimiD· 1 shared Hua YangiD· 1 shared Li Juan WuiD· 1 shared Pak‐Hin Hinson CheungiD· 1 shared Shravya HonneiD· 1 shared Stanley M. PerlmaniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperMicrobiology

Baek KimORCID

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1 paper

Recent·Most cited

SAMHD1 promotes SARS-CoV-2 infection by enhancing HNF1-dependent ACE2 expression in lung epithelial cells

Pak‐Hin Hinson Cheung, Pearl Chan, Hua Yang, Shravya Honne, Baek Kim, Stanley M. Perlman, Li Juan Wu

This study shows SAMHD1 promotes SARS-CoV-2 infection in lung epithelial cells by enhancing ACE2 expression through HNF1 and HNF1β, independent of its IFN-suppressive function.

bioRxiv · Oct 23, 2025 · PreprintMicrobiology