Li Juan Wu

This paper identifies SAMHD1's role in enhancing HIV-1-induced glycolysis in monocytic cells through upregulation of hexokinase 2.

This study identifies c-MET as a host factor that HIV-1 exploits to enhance viral entry and replication in primary CD4+ T cells by upregulating c-MET and modulating receptor expression and signaling pathways.

This study evaluates three METTL3 inhibitors' effects on reducing m6A levels and HIV-1 latency reversal in CD4+ T cells, finding differential potency and cytotoxicity.

This study investigates the role of m6A machinery in HIV-1 replication in primary CD4+ T cells, finding that auxiliary m6A writer complex members and the reader YTHDF2 significantly impact viral replication, while catalytic core components have minimal effect.

This study shows SAMHD1 promotes SARS-CoV-2 infection in lung epithelial cells by enhancing ACE2 expression through HNF1 and HNF1β, independent of its IFN-suppressive function.

This study identifies m6A RNA modifications and their role in HIV-1 infection of primary CD4+ T cells, showing cell-type specific effects on PLIN3 expression and HIV-1 production.

This study shows SAMHD1 enhances HIV-1-induced apoptosis in monocytic cells through the mitochondrial pathway by reducing mitochondrial membrane potential and promoting cytochrome c release.

This study shows influenza virus weakens neutrophil capture of low-virulence Streptococcus pneumoniae by reducing capsule receptor-mediated complement activation, enhancing bacterial survival and virulence.