Pak‐Hin Hinson Cheung

This paper identifies SAMHD1's role in enhancing HIV-1-induced glycolysis in monocytic cells through upregulation of hexokinase 2.

This study shows SAMHD1 promotes SARS-CoV-2 infection in lung epithelial cells by enhancing ACE2 expression through HNF1 and HNF1β, independent of its IFN-suppressive function.

This study shows SAMHD1 enhances HIV-1-induced apoptosis in monocytic cells through the mitochondrial pathway by reducing mitochondrial membrane potential and promoting cytochrome c release.