MicrobiologybioRxivPreprint
SAMHD1 promotes SARS-CoV-2 infection by enhancing HNF1-dependent ACE2 expression in lung epithelial cells
Pak‐Hin Hinson Cheung, Pearl Chan, Hua Yang…·Li Juan Wu
This study shows SAMHD1 promotes SARS-CoV-2 infection in lung epithelial cells by enhancing ACE2 expression through HNF1 and HNF1β, independent of its IFN-suppressive function.
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