DNAJC13 restricts TLR7-driven autoimmunity in mice and humans
Victoria E. Rael, Julian A. Yano, Leianna C. Slayden, Allison W. Roberts, Ben F. Brian, Pedro Ruivo, Laura B. Lewandowski, Linda T. Hiraki, Gregory M. Barton
This study identifies DNAJC13 as a critical regulator of TLR7 trafficking and shows its role in preventing autoimmunity in mice and humans.
bioRxiv · Oct 19, 2026 · PreprintImmunology