Nan Qin

CCR2 is a potential biomarker and therapeutic target in Group 3 medulloblastoma

This study identifies CCR2 as a biomarker and therapeutic target in Group 3 medulloblastoma, showing its association with dissemination and poor survival, and demonstrating therapeutic efficacy through Cenicriviroc.

Transcriptome and metabolome analyses reveal novel genetic targets for L-tryptophan overproduction in Corynebacterium glutamicum

The paper identifies two genetic targets, glnK and sugR, that enhance L-tryptophan production in Corynebacterium glutamicum through transcriptome and metabolome analyses.

Linker histone H1-0 is a specific mediator of the repressive ETV6::RUNX1 transcriptional landscape

This study identifies H1-0 as a mediator of ETV6::RUNX1-induced quiescence in BCP-ALL preleukemic cells and suggests HDACi treatment as a potential therapeutic approach.