Author

Gregory M. Barton

Howard Hughes Medical InstituteORCID 0000-0002-3793-0100Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Andrew Ly· 2 shared Ali ToutiD· 1 shared Allison W. RobertsiD· 1 shared Allon WagneriD· 1 shared Ashley K. Liu· 1 shared Ben F. BrianiD· 1 shared Cammie F. LesseriD· 1 shared Charlotte A. LangneriD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersImmunology

Andrew Ly

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Author profile →

4 papers

Recent·Most cited

DNAJC13 restricts TLR7-driven autoimmunity in mice and humans

Victoria E. Rael, Julian A. Yano, Leianna C. Slayden, Allison W. Roberts, Ben F. Brian, Pedro Ruivo, Laura B. Lewandowski, Linda T. Hiraki, Gregory M. Barton

This study identifies DNAJC13 as a critical regulator of TLR7 trafficking and shows its role in preventing autoimmunity in mice and humans.

bioRxiv · Oct 19, 2026 · PreprintImmunology

Profiling of intestinal T cells reveals antigen-specific dependency on early-life programming for the generation of microbiota-reactive Tregs

Lara Vetter, Jessica N. Witchley, So Hyun Ahn, R. Camille Brewer, Andrew Ly, Ali Tout, Allon Wagner, Gregory M. Barton

This study profiles intestinal T cell responses to the microbiota, revealing antigen-specific dependencies on early-life programming for generating microbiota-reactive Tregs.

bioRxiv · Sep 29, 2026 · PreprintImmunology

Identification of distinct cDC2 subpopulations that direct microbiota-specific T cell differentiation

Shaina L. Carroll, Andrew Ly, Ashley K. Liu, Maria Cecília Campos Canesso, Gabriel D. Victora, Daniel Mucida, Gregory M. Barton

The paper identifies distinct cDC2 subpopulations that direct microbiota-specific T cell differentiation through varied interactions.

bioRxiv · Nov 4, 2025 · PreprintImmunology

Macrophages orchestrate elimination of Shigella from the intestinal epithelial cell niche via TLR-induced IL-12 and IFN-γ

Kevin Eislmayr, Charlotte A. Langner, Fitty L Liu, Sudyut Yuvaraj, Janet Peace Babirye, Justin L. Roncaioli, Jenna Vickery, Gregory M. Barton, Cammie F. Lesser, Russell E. Vance

This study identifies macrophages, not neutrophils, as key in controlling Shigella through TLR-induced IL-12 and IFN-γ in a mouse model of shigellosis.

Cell Host & Microbe · Aug 29, 2025Peer-reviewedImmunology