Chronic Paraventricular OX1R Overexpression Induces Oxidative Stress and Hypertension in Rats
Peiying Huang, Nasibeh Yousefzadehkharvanagh, Derrick Simet, Xinqian Chen, Yingli Li, Robert A. Larson, Lanrong Bi, Qinghui Chen, Bojun Chen, Zhiying Jenny Shan
This study shows that chronic overexpression of OX1R in the PVN of rats leads to hypertension, oxidative stress, and increased sympathetic activity.
bioRxiv · Feb 11, 2026 · PreprintPhysiology