Author

Per-Henrik Helgesson

Novavax (Sweden)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Anna-Karin E. PalmiD· 1 shared Behdad Zarnegar· 1 shared Berit CarowiD· 1 shared Carolina Lunderius-Andersson· 1 shared Emelie Bringeland· 1 shared Eray Akpinar· 1 shared Eva Spennare· 1 shared Ingrid Lekberg Osterman· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Anna-Karin E. PalmORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

Matrix-M(R) adjuvant triggers inflammasome activation and enables antigen cross-presentation through induction of lysosomal membrane permeabilization

Behdad Zarnegar, Berit Carow, Jens Eriksson, Eva Spennare, Pontus Öhlund, Eray Akpinar, Emelie Bringeland, Ingrid Lekberg Osterman, Lena Lundqvist, Johanna Antti, Niklas Handin, Per-Henrik Helgesson, Johan Bankefors, Karin Lövgren Bengtsson, Mikael E. Sellin, , Carolina Lunderius-Andersson

This study shows Matrix-M adjuvant induces lysosomal membrane permeabilization, enabling antigen cross-presentation and IL-1β/IL-18 secretion, which contributes to its adjuvant effect.

npj Vaccines · Aug 5, 2025Peer-reviewedImmunology