Protein kinase CK2 alpha prime as a dual modulator of neuroimmune signaling and synaptic dysfunction in Tauopathy
Angel White, Peter Gavrilyuk, Persephone Gu, Rafael Falcon Moya, Reid Thurston, Amal Fickak, Nicholas B Rozema, Prarthana Keshavaram, Scott Vermilyea, Riley Schlichte, Joyce P. Meints, Ying Zhang, Alfonso Araque, Michael K. Lee, Rocío Gómez‐Pastor
This study identifies CK2 as a regulator of tauopathy by modulating tau phosphorylation, neuroinflammation, and synaptic dysfunction in mice.
bioRxiv · Jun 24, 2025 · PreprintNeuroscience