MCL-1 as a molecular switch between myofibroblastic and pro-angiogenic features of breast cancer-associated fibroblasts
Chloé C. Lefebvre, Philippine Giowachini, Jennifer Derrien, Maxime Naour, Isabelle Corre, Laura Thirouard, Elise Douillard, David Chiron, François Guillonneau, Lucas Treps, Mario Campone, Philippe Paul Juin, Frédérique Souazé
This study shows that MCL-1 regulates the switch between myofibroblastic and pro-angiogenic features in breast cancer-associated fibroblasts, with implications for treatment response.
Cell Death and Disease · Aug 9, 2025Peer-reviewedCancer Biology