Author

Jennifer Derrien

Centre National de la Recherche ScientifiqueORCID 0000-0002-3135-2055Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Elise Douillard· 2 shared Mario CamponeiD· 2 shared Philippe Paul JuiniD· 2 shared Aurore M. M. Dupuy· 1 shared Camille E. Tessier· 1 shared Camille El Harrif· 1 shared Chloé C. LefebvreiD· 1 shared Claude PrigentiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Elise Douillard

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2 papers

Recent·Most cited

Cancer BiologyEMBO Molecular MedicinePeer-reviewedAug 26, 2025

Primary cilia promote EMT-induced triple-negative breast tumor heterogeneity and resistance to therapy

Camille E. Tessier, Jennifer Derrien, Aurore M. M. Dupuy…·Vincent J. Guen

This study shows primary cilia in TNBC cells contribute to chemoresistance by supporting EMT-driven heterogeneity and stemness, and inhibiting ciliogenesis reduces this resistance.

10 citationstop 4%

humanorganoid / primary culture

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Cancer BiologyCell Death and DiseasePeer-reviewedAug 9, 2025

MCL-1 as a molecular switch between myofibroblastic and pro-angiogenic features of breast cancer-associated fibroblasts

Chloé C. Lefebvre, Philippine Giowachini, Jennifer Derrien…·Frédérique Souazé

This study shows that MCL-1 regulates the switch between myofibroblastic and pro-angiogenic features in breast cancer-associated fibroblasts, with implications for treatment response.

4 citations

humanbulk RNA-seq

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