François Guillonneau

This study identifies CK1 as a regulator of lysosomal fitness and ferroptotic sensitivity in glioblastoma stem-like cells through molecular glue degraders.

This study investigates the pathogenic effects of the DES p.R406W mutation, showing it causes electrical and structural heart remodeling linked to arrhythmias and sudden cardiac death.

This study identifies CK1 as a bimodal regulator of the cGAS-STING pathway, showing it both promotes DNA sensing and facilitates signaling termination, with therapeutic implications for cancer.

The paper identifies an EGFR/TBK1-dependent mitochondrial quality control mechanism that contributes to acquired resistance to temozolomide in glioma cells.

The paper shows that tunneling nanotubes (TNTs) transfer preneoplastic signals via BMP-dependent pathways in breast cells, promoting transformation in non-transformed cells.

This study shows that MCL-1 regulates the switch between myofibroblastic and pro-angiogenic features in breast cancer-associated fibroblasts, with implications for treatment response.

The paper identifies PfEMP1 variants in Plasmodium falciparum field isolates using proteogenomic methods and mass spectrometry, linking them to clinical malaria outcomes.

This paper analyzes the chicken erythroblast proteome during terminal differentiation, revealing both conserved and divergent protein expression patterns compared to human erythroblasts.