Author

David Chiron

Centre National de la Recherche ScientifiqueORCID 0000-0002-2199-752XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Chloé C. LefebvreiD· 1 shared Elise Douillard· 1 shared François GuillonneauiD· 1 shared Frédérique SouazéiD· 1 shared Isabelle CorreiD· 1 shared Jennifer DerrieniD· 1 shared Laura ThirouardiD· 1 shared Lucas TrepsiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Chloé C. LefebvreORCID

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1 paper

Recent·Most cited

MCL-1 as a molecular switch between myofibroblastic and pro-angiogenic features of breast cancer-associated fibroblasts

Chloé C. Lefebvre, Philippine Giowachini, Jennifer Derrien, Maxime Naour, Isabelle Corre, Laura Thirouard, Elise Douillard, David Chiron, François Guillonneau, Lucas Treps, Mario Campone, Philippe Paul Juin, Frédérique Souazé

This study shows that MCL-1 regulates the switch between myofibroblastic and pro-angiogenic features in breast cancer-associated fibroblasts, with implications for treatment response.

Cell Death and Disease · Aug 9, 2025Peer-reviewedCancer Biology