Lucas Treps

This paper develops IFNAR1 antagonists that selectively block IFNAR signaling in tumor cells, enhancing VSV oncolytic activity in mesothelioma and melanoma models.

This study develops a vascularized mesothelioma-on-chip model to evaluate oncolytic measles virus effects on the tumor microenvironment.

This study identifies a complement-inflammasome signaling axis that drives excessive inflammation during Pseudomonas aeruginosa and Aspergillus fumigatus co-infection in cystic fibrosis patients.

This study investigates how NSCLC cells reprogram endothelial cells into tumor endothelial cells, altering immune cell behavior in vitro.

This study shows that MCL-1 regulates the switch between myofibroblastic and pro-angiogenic features in breast cancer-associated fibroblasts, with implications for treatment response.