ImmunologyPLoS PathogensPeer-reviewed
The Inflammasome Pathway is Activated by Dengue Virus Non-structural Protein 1 and is Protective During Dengue Virus Infection
Marcus P. Wong, Evan Y. W. Juan, Sai S. Chelluri…·Eva Harris
This study shows DENV NS1 activates inflammasomes in macrophages, leading to IL-1β release without pyroptosis, and that this pathway is protective against DENV infection.