Single-Cell Transcriptomics Reveals Dynamics of NK Cell Expansion in a Feeder Cell-Free Culture of PBMCs - Implications for Immunotherapy
Brian Ladd, Markella Zacharouli, Per-Henrik Holmqvist, Stefanie Renken, Pontus Blomberg, Véronique Chotteau
This study uses single-cell transcriptomics to analyze NK cell expansion in PBMC cultures, identifying factors influencing donor variability and suggesting strategies to improve NK cell fraction and expansion.
Cytotherapy · Oct 25, 2025Peer-reviewedBioengineering