Author

Portia A. Kreiger

Children's Hospital of Philadelphia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Edward M. BehrensiD· 2 shared Amy E. BaxteriD· 1 shared Angela Ge· 1 shared Chhanda Biswas· 1 shared Connie JiangiD· 1 shared David Smith· 1 shared Derek A. OldridgeiD· 1 shared Dokyoon KimiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersImmunology

Edward M. BehrensORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintOct 14, 2026

Decomposing scanner batch effects and their impact on pathology foundation models

Jonghyun Lee, Lina Takemaru, Yutong Zhu…·Derek A. Oldridge

This study decomposes scanner batch effects in pathology foundation models and shows that image corrections based on measured properties improve alignment but do not fully match model representations.

DOI 10.64898/2026.10.07.757122

imagingstatistical model

𝕏 PostBluesky

ImmunologybioRxivPreprintMar 15, 2026

Damaged glomeruli in proliferative pediatric lupus nephritis exhibit a C5a-C5aR1 induced fibrotic transcriptional program

Sarah McCuaig, Easton Elliott, Seth Anderson…·Edward M. Behrens

The paper identifies a C5a-C5aR1 signaling pathway driving fibrosis in damaged glomeruli of pediatric lupus nephritis using spatial transcriptomics and bulk RNA-seq.

DOI 10.64898/2026.03.12.711136

humanspatial transcriptomics

𝕏 PostBluesky

ImmunologyJournal of Leukocyte BiologyPeer-reviewedOct 11, 2024

Transcription Factor NRF2 is Activated by Erythrophagocytosis of Oxidized Red Blood Cell Products and Suppresses the IL-12-IFNg-IL-10 Axis in a Murine Model of Hyperinflammatory Disease

Paul M Gallo, Em Elliott, Grace C Ford…·Edward M. Behrens

This study shows that NRF2 activation by erythrophagocytosis suppresses the IL-12-IFNg-IL-10 axis, reducing hyperinflammation in a murine model of hyperinflammatory disease.

2 citations

mouseproteomics

𝕏 PostBluesky