Identification of bioactive metabolites in human iPSC-derived dopaminergic neurons with PARK2 mutation: altered mitochondrial and energy metabolism.
Justyna Okarmus, Jesper Foged Havelund, Matias Ryding, Sissel Ida Schmidt, Helle Bogetofte, Rachel Heon‐Roberts, Richard Wade‐Martins, Sally A. Cowley, Brent James Ryan, Nils Joakim Færgeman, Poul Hyttel, Morten Meyer
This study identifies altered mitochondrial and energy metabolism in PARK2 mutant human iPSC-derived dopaminergic neurons through metabolomic analysis.
Stem Cell Reports · May 27, 2021Peer-reviewedNeuroscience