Justyna Okarmus

This study shows simvastatin reduces PD-related phenotypes in iPSC-derived neurons by inhibiting RhoA, with RhoA activity varying across PD subtypes.

The paper shows USP30 inhibition enhances mitophagy and reduces oxidative stress in parkin-deficient neurons, with non-dopaminergic neurons being the main受益者.

This study identifies altered mitochondrial and energy metabolism in PARK2 mutant human iPSC-derived dopaminergic neurons through metabolomic analysis.

This study shows that anti-IgLON5 antibodies cause functional and neurodegenerative changes in human neurons, leading to cell death, supporting their role in the disease.

This study investigates lysosomal alterations in PARK2 knockout dopaminergic neurons derived from iPSCs, revealing links between parkin deficiency and lysosomal dysfunction in Parkinson's disease.