Author

Pouria Farkhondehkish

Uppsala University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:phylogenetics / evolution· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Eva AnderssoniD· 2 shared Filip MihaličiD· 2 shared Per JemthiD· 2 shared Dahiana ArcilaiD· 1 shared Emma ÅbergiD· 1 shared Leif AnderssoniD· 1 shared Mats E. PetterssoniD· 1 shared Niels Theys· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 28 mutual co-author links

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2 shared papersMolecular Biology

Eva AnderssonORCID

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2 papers

Recent·Most cited

Conservation of affinity rather than sequence underlies a dynamic evolution of the motif-mediated p53/MDM2 interaction in teleosts

Filip Mihalič, Dahiana Arcila, Mats E. Pettersson, Pouria Farkhondehkish, Eva Andersson, Leif Andersson, Ricardo Betancur‐R, Per Jemth

The paper investigates the evolution of p53/MDM2 interaction in teleosts, finding that affinity is conserved through compensatory changes in both conserved and non-conserved regions.

Molecular Biology and Evolution · Jan 31, 2024Peer-reviewedMolecular Biology

Evolution of affinity between p53 and MDM2 across the animal kingdom demonstrates high plasticity of motif-mediated interactions

Filip Mihalič, Emma Åberg, Pouria Farkhondehkish, Niels Theys, Eva Andersson, Per Jemth

The paper examines the evolution of p53/MDM2 interaction affinity across species, finding significant variation in binding strength and suggesting plasticity in motif-mediated interactions.

Protein Science · May 22, 2023Peer-reviewedMolecular Biology