Core and Flanking bHLH-PAS:DNA interactions mediate specificity and drive obesity
David C. Bersten, Adrienne E. Sullivan, Daniel P. McDougal, James Breen, Rebecca L. Fitzsimmons, George E.O. Muscat, Stephen Pederson, John B. Bruning, Chen‐Ming Fan, PQ Thomas, DL Russell, Daniel J. Peet, Murray L. Whitelaw
The paper identifies core and flanking DNA interactions in bHLH-PAS transcription factors that determine binding specificity and link to obesity.
bioRxiv · Feb 1, 2022 · PreprintMolecular Biology