Author

Prabhat R. Napit

Children's Hospital of Philadelphia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adeline L. VanderveriD· 2 shared Akshata Almad· 2 shared Anjali Bhagavatula· 2 shared Asako TakanohashiiD· 2 shared Judith B. GrinspaniD· 2 shared Julia Liao HackeriD· 2 shared Sunetra Sase· 2 shared Alyssa L. GagneiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersNeuroscience

Adeline L. VanderverORCID

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2 papers

Recent·Most cited

Deletion of TUBB4A mitigates the oligodendrocyte and neuronal deficits in human iPSCs derived from individuals affected by H-ABC

Zhongqi Hou, Rolf Dale Bates, Prabhat R. Napit, Luis Garcia, Anjali Bhagavatula, Julia Liao Hacker, Teshawn Johnson, Alyssa L. Gagne, Jean Ann Maguire, Asako Takanohashi, Deborah L. French, Akshata Almad, Judith B. Grinspan, Adeline L. Vanderver, Sunetra Sase

This study shows that deleting TUBB4A in human iPSCs reduces cell-autonomous deficits in oligodendrocytes and neurons associated with H-ABC, suggesting it could be a therapeutic strategy for TUBB4A-related leukodystrophy.

bioRxiv · Aug 6, 2026 · PreprintNeuroscience

Therapeutic suppression of Tubb4a rescues H-ABC leukodystrophy

Sunetra Sase, Julia Liao Hacker, Prabhat R. Napit, Anjali Bhagavatula, Sarah Woidill, Annemarie D’Alessandro, Marisa A. Jeffries, Akshata Almad, Asako Takanohashi, Quasar Saleem Padiath, Judith B. Grinspan, Eric D. Marsh, Adeline L. Vanderver

This study shows that suppressing Tubb4a with an ASO improves symptoms and extends lifespan in a mouse model of H-ABC leukodystrophy.

Molecular Therapy · Jan 20, 2026Peer-reviewedNeuroscience