Partial sleep deprivation diminishes and uncouples neuronal activity and energy metabolism in the live mouse hippocampus
Zhengyi Lu, Kevin Mai, Alfredo Cárdenas Rivera, Chang Liu, Yuntao Li, Priya Shah, Kai Zhang, Bryan Q. Spring, Mohammad Abbas Yaseen
This study shows that partial sleep deprivation reduces and uncouples neuronal activity and oxygen levels in the mouse hippocampus, with effects persisting after recovery.
bioRxiv · Oct 1, 2026 · PreprintNeuroscience