Author

Mukund Iyer

University of Southern California

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Aaron G. BaughiD· 2 shared Evanthia T. Roussos TorresiD· 2 shared Josh NemaniD· 2 shared Adam L. MacLeaniD· 1 shared Alex LeeiD· 1 shared Batul Al-ZubeidyiD· 1 shared Brooke Naomi NakamuraiD· 1 shared Cheol H. ParkiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Aaron G. BaughORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A class act: HDAC1-Malat1 regulates MDSC apoptosis and cell cycling to decrease suppression of T cells

Aaron G. Baugh, Yingtong Liu, Edgar Gonzalez, Batul Al-Zubeidy, Mukund Iyer, Alex Lee, Nana Gyabaah-Kessie, Matthew B. Jacobo, Cheol H. Park, Jesse Kreger, Lori Khatchaturian, Sabrina K. Zhong, Kaliya Acevedo, Saul J. Priceman, Josh Neman, , Evanthia T. Roussos Torres

The paper shows HDAC1 inhibition in MDSCs increases Malat1, decreases pSTAT3, induces apoptosis and cell cycle arrest, and reduces T cell suppression.

bioRxiv · Mar 25, 2026 · PreprintImmunology

Targeting MDSC-HTR2B to Improve Immune Checkpoint Inhibitors in Breast to Brain Metastasis

Mukund Iyer, Diganta Das, Aaron G. Baugh, Priya Shah, Brooke Naomi Nakamura, Saman Sedighi, Max Reed, Julie K. Jang, Frances Elaine Chow, Evanthia T. Roussos Torres, Josh Neman

The paper identifies HTR2B on MDSCs as a target to enhance immune checkpoint inhibitors in breast-to-brain metastasis using clozapine and anti-PD-1 therapy.

bioRxiv · Jun 20, 2024 · PreprintCancer Biology