A novel algorithm for the collective integration of single cell RNA-seq during embryogenesis
Wuming Gong, Bhairab N. Singh, Pruthvi Shah, Satyabrata Das, Joshua W. M. Theisen, Sunny Sun-Kin Chan, Michael Kyba, Mary G. Garry, Demetris Yannopoulos, Wei Pan, Daniel J. Garry
This paper introduces a novel algorithm to integrate heterogeneous temporal scRNA-seq datasets and reconstruct lineage trajectories, identifying Ebf1 as a key transcription factor for mouse endothelial development.
bioRxiv · Feb 7, 2019 · PreprintBioinformatics