Age-dependent Changes in a Chaperone Complex in the Mouse Heart
Purnima Devaki Bhat, Aswan Nalli, Luke J. Shoemaker, Jennifer Q. Kwong, Hiroshi Qadota, Prasanna Krishnamurthy, Guy M. Benian
This study shows that in aging mouse hearts, Unc45b and Hsp70 levels decline at the protein level, while Hsp90 remains stable, potentially contributing to age-related cardiomyopathies.
bioRxiv · Sep 12, 2024 · PreprintCell Biology