Jennifer Q. Kwong

This study shows that SLC25A1 in cardiomyocytes regulates differentiation, mitochondrial function, and cardiac development, linking mitochondrial citrate export to developmental gene programs.

The paper identifies haploinsufficient genes MRPL40 and SLC25A1 in the 22q11.2 locus and shows their genetic interactions contribute to cardiac and brain phenotypes in mice.

This study shows meclizine improves cardiac function and mitochondrial structure in a mitochondrial disease model without relying on ATP or glycolysis.

This study shows that in aging mouse hearts, Unc45b and Hsp70 levels decline at the protein level, while Hsp90 remains stable, potentially contributing to age-related cardiomyopathies.

This study identifies SLC25A1 as a dosage-dependent regulator of metabolic reprogramming and heart development, linking mitochondrial function to cardiac morphogenesis and congenital heart disease.

The paper identifies a mitochondrial transporter interactome disruption in 22q11.2 syndrome, linking it to synapse function and behavior.