Author

Luke J. Shoemaker

Emory University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Jennifer Q. KwongiD· 2 shared Andrew PymaniD· 1 shared Aswan Nalli· 1 shared Benjamin Xiongzheng HuangiD· 1 shared Darrell P. ChandleriD· 1 shared Guy M. BenianiD· 1 shared Hiroshi QadotaiD· 1 shared Hyoungjoo LeeiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersPhysiology

Jennifer Q. KwongORCID

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Author profile →

3 papers

Recent·Most cited

SATB2 and circ3915 RNA chromatin dysregulation drive KRAS-like oncogenic transformation

Rebekah Eleazer, Smitha George, Luke J. Shoemaker, Wesley N. Saintilnord, Richard N Cassidy, Andrew Pyman, Kin Lau, Molly T. Soper-Hopper, Hyoungjoo Lee, Darrell P. Chandler, Yvonne N. Fondufe‐Mittendorf

This study shows that SATB2 and circ3915 RNA chromatin dysregulation can drive KRAS-like oncogenic transformation in lung epithelial cells without driver mutations.

Cell Communication and Signaling · Jun 24, 2026Peer-reviewedCancer Biology

Meclizine rescues cardiac function and mitochondrial ultrastructure by ATP- and glycolysis-independent mechanisms in a genetic model of mitochondrial energy dysfunction

Nasab Ghazal, Benjamin Xiongzheng Huang, Luke J. Shoemaker, Victor Faúndez, Jennifer Q. Kwong

This study shows meclizine improves cardiac function and mitochondrial structure in a mitochondrial disease model without relying on ATP or glycolysis.

bioRxiv · Sep 3, 2025 · PreprintPhysiology

Age-dependent Changes in a Chaperone Complex in the Mouse Heart

Purnima Devaki Bhat, Aswan Nalli, Luke J. Shoemaker, Jennifer Q. Kwong, Hiroshi Qadota, Prasanna Krishnamurthy, Guy M. Benian

This study shows that in aging mouse hearts, Unc45b and Hsp70 levels decline at the protein level, while Hsp90 remains stable, potentially contributing to age-related cardiomyopathies.

bioRxiv · Sep 12, 2024 · PreprintCell Biology