Author

Qian Qu

Shanghai Jiao Tong University

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Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:yeast· 1

Frequent Co-Authors

Huasong AiiD· 1 shared Lei LiuiD· 1 shared Maoshen SuniD· 1 shared Xiangwei WuiD· 1 shared Yunxiang DuiD· 1 shared Zhengqing LiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperMolecular Biology

Huasong AiORCID

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1 paper

Recent·Most cited

Mechanistic Insights into the Stimulation of the Histone H3K9 Methyltransferase Clr4 by Proximal H3K14 Ubiquitination

Yunxiang Du, Maoshen Sun, Zhengqing Li, Xiangwei Wu, Qian Qu, Huasong Ai, Lei Liu

The paper determines the crystal structures of Clr4 bound to ubiquitinated and unmodified H3 peptides, revealing how H3K14 ubiquitination synergistically enhances Clr4 catalytic activity through conformational changes and multivalent interactions.

Science Advances · May 30, 2025Peer-reviewedMolecular Biology