Genome-wide association and gene-virus interaction study of liver disease in hepatitis C virus-infected patients
Jocelyn Quistrebert, Haiting Chai, Yan Chen, Narayan Ramamurthy, Hamish A. Innes, Jennifer Benselin, Zhiqing Wang, Qijing Shen, Emanuele Marchi, Vincent Pedergnana, Paul Klenerman, Graham Cooke, Eleanor J. Barnes, William Lucien Irving, John McLauchlan, M. Azim Ansari
This study identifies genetic risk factors and host-viral interactions for cirrhosis progression in hepatitis C virus-infected patients but finds no genome-wide significant associations for hepatocellular carcinoma.
medRxiv · Oct 12, 2025 · PreprintGenetic & Genomic Medicine