Author

Graham Cooke

Imperial College LondonORCID 0000-0001-6475-5056Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Research Focus:GWAS / association mapping· 2 Organism:human· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Approach:benchmark study· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Eleanor J. BarnesiD· 2 shared John McLauchlaniD· 2 shared M. Azim AnsariiD· 2 shared William Lucien IrvingiD· 2 shared Akamol E. SuvarnapunyaiD· 1 shared Anan Bzami· 1 shared Anna Rýdlová· 1 shared Blanca M. Perez-SepulvedaiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Eleanor J. BarnesORCID

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Author profile →

3 papers

Recent·Most cited

Genome-wide association and gene-virus interaction study of liver disease in hepatitis C virus-infected patients

Jocelyn Quistrebert, Haiting Chai, Yan Chen, Narayan Ramamurthy, Hamish A. Innes, Jennifer Benselin, Zhiqing Wang, Qijing Shen, Emanuele Marchi, Vincent Pedergnana, Paul Klenerman, Graham Cooke, Eleanor J. Barnes, William Lucien Irving, John McLauchlan, M. Azim Ansari

This study identifies genetic risk factors and host-viral interactions for cirrhosis progression in hepatitis C virus-infected patients but finds no genome-wide significant associations for hepatocellular carcinoma.

medRxiv · Oct 12, 2025 · PreprintGenetic & Genomic Medicine

Comparative phenotypic, genomic and transcriptomic characterisation of two Salmonella Typhimurium strains for a first-in-human challenge model

Christopher Smith, Anan Bzami, Xiaojun Zhu, Jessica A. White, Nerie Roa, Akamol E. Suvarnapunya, Emma Smith, Anna Rýdlová, Robert Varro, Zainab Kiliddar, Lijuan Luo, Blanca M. Perez-Sepulveda, Melita A. Gordon, Graham Cooke, Robert K. M. Choy, , Malick M. Gibani

The paper characterizes two Salmonella Typhimurium strains for a first-in-human challenge model, confirming their genomic and phenotypic stability post-manufacture.

bioRxiv · Apr 24, 2025 · PreprintMicrobiology

Impact of virus subtype and host IFNL4 genotype on large-scale RNA structure formation in the genome of hepatitis C virus

Peter Simmonds K, Lize Cuypers, William Lucien Irving, John McLauchlan, Graham Cooke, Eleanor J. Barnes, M. Azim Ansari

The paper examines how HCV virus subtype and host IFNL4 genotype influence genome-scale RNA structure formation and compositional features in HCV.

RNA · Aug 3, 2020Peer-reviewedGenomics