Author

Qingmin Ruan

Huazhong Agricultural University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Research Focus:perturbation response prediction· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Jin HeiD· 2 shared Na TianiD· 2 shared Yuyang NiiD· 2 shared Dingqi LiuiD· 1 shared Xinyu ShiiD· 1 shared Xinyu ShiiD· 1 shared Xun WangiD· 1 shared Xun WangiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 27 mutual co-author links

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2 shared papersSynthetic Biology

Jin HeORCID

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2 papers

Recent·Most cited

Establishing a Retron-Based Cytosine Base Editor for Targeted Hypermutation in Escherichia coli

Xinyu Shi, Yuyang Ni, Na Tian, Qingmin Ruan, Dingqi Liu, Jin He, Xun Wang

This paper develops a retron-based cytosine base editor (RCBE) that enables both C to T and G to A conversions in Escherichia coli, achieving a mutation rate of up to 0.2% in GC-rich regions.

bioRxiv · Jun 20, 2026 · PreprintSynthetic Biology

Reducing competition between msd and genomic DNA significantly improved the editing efficiency of the retron editing system

Yuyang Ni, Yifei Wang, Xinyu Shi, Qingmin Ruan, Na Tian, Jin He, Xun Wang

This study improves retron-based gene editing efficiency by reducing competition between msDNA and genomic DNA, achieving 100% editing efficiency.

bioRxiv · Jun 4, 2024 · PreprintSynthetic Biology