Author

Yuyang Ni

Shangrao Normal UniversityORCID 0009-0009-6851-4028Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Research Focus:perturbation response prediction· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Jin HeiD· 2 shared Na TianiD· 2 shared Qingmin Ruan· 2 shared Dingqi LiuiD· 1 shared Xinyu ShiiD· 1 shared Xinyu ShiiD· 1 shared Xun WangiD· 1 shared Xun WangiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 27 mutual co-author links

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2 shared papersSynthetic Biology

Jin HeORCID

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintJun 20, 2026

Establishing a Retron-Based Cytosine Base Editor for Targeted Hypermutation in Escherichia coli

Xinyu Shi, Yuyang Ni, Na Tian…·Xun Wang

This paper develops a retron-based cytosine base editor (RCBE) that enables both C to T and G to A conversions in Escherichia coli, achieving a mutation rate of up to 0.2% in GC-rich regions.

DOI 10.64898/2026.06.18.733067

E. coliexperimental assay

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Synthetic BiologybioRxivPreprintJun 4, 2024

Reducing competition between msd and genomic DNA significantly improved the editing efficiency of the retron editing system

Yuyang Ni, Yifei Wang, Xinyu Shi…·Xun Wang

This study improves retron-based gene editing efficiency by reducing competition between msDNA and genomic DNA, achieving 100% editing efficiency.

1 citation

CRISPR screenexperimental assay

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