A Highly Efficient Aorta-Gonad-Mesonephros-Like Definitive Hemogenic Endothelium From Human Pluripotent Stem Cells
Yesai S. Fstkchyan, Qingwen Cheng, Jingli Zhang, Daniel Lu, Guanyi Huang, Tiange Dong, Lauren G. Jones, Matt Kanke, Chris Hale, Kristin V. Tarbell, Chi-Ming Li, Songli Wang, Stuart M. Chambers
This paper describes a method to efficiently generate definitive hemogenic endothelium from human pluripotent stem cells, which can differentiate into hematopoietic progenitors and stem cells with multilineage potential.
bioRxiv · Jun 26, 2023 · PreprintDevelopmental Biology